EASI.DONG HUN LEE LABSEOUL NATIONAL UNIVERSITYEpigenetics, Aging & Skin Inflammation
KREN
Research Stories

Beyond the result.
The question and the evidence.

Questions that need more than one method. Explore how our featured studies connect clinical observations, integrative analysis and functional experiments.

Selected publications and Research Stories feature papers in which Dong Hun Lee is a first or corresponding author, including shared first and corresponding authorship.

Original Figure 6a–f: FOXP3 UMAP, Treg frequencies and TNFRSF4 analysis in public skin single-cell data; DAPI/CD4/FOXP3/OX40 skin immunofluorescence in controls and AD, with quantification. Scale bars: 40 μm.01
2026 / Inflammatory Skin Disease

When more regulatory T cells do not mean better control

Do expanded regulatory T cells in atopic dermatitis retain effective suppression, or do they contain distinct functional states?

Co-corresponding author collaboration
  • Yong-Hee KimPB Immune Therapeutics Inc · Transplantation Research Institute, Seoul National University Medical Research Center
  • Hyun Je KimDepartment of Microbiology and Immunology, Seoul National University College of Medicine
Read the research story
Original Figure 2A–B: overlap and differential patterns of DEGs across HDAC4 perturbation, UV-induced senescence and H2O2-induced senescence.02
2022 / Epigenetic Skin Aging

Tracing a skin-aging signal from HDAC4 to DDIT4

Which genes and cellular changes connect reduced HDAC4 to stress-induced senescence in skin fibroblasts?

Co-corresponding author collaboration
  • Daehee HwangDepartment of Biological Sciences, Seoul National University
  • Jin Ho ChungDepartment of Dermatology, Seoul National University College of Medicine
Read the research story
Hippocampal DCX, Ki-67 and DAPI staining in control mice and mice exposed to chronic skin UV irradiation. Scale bar: 150 μm.03
2024 / Skin–Brain Interaction

Dopamine signaling between skin exposure and memory

Which signals connect repeated UV exposure of the skin with changes in brain function?

Co-corresponding author collaboration
  • Jin Ho ChungDepartment of Dermatology, Seoul National University Hospital, Seoul National University College of Medicine
  • Yong-Seok LeeDepartment of Physiology, Seoul National University College of Medicine
Read the research story
01 / Research StoriesThe questions behind the papers02 / Methods & ExpertiseMethods connected by a question03 / CollaborateThe next question, together
Students · Researchers · Industry partners

A question we could
answer together?

Skin aging and epigenomics, inflammatory skin disease, skin–brain interaction, medical devices and EBD. Get in touch—even at the earliest idea stage.

We welcome prospective students and interns, and collaboration proposals from researchers, clinicians and industry partners.

Propose a collaboration Student opportunities